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Aging and Mitochondrial Function L-Carnitine plays a critical role in maintaining mitochondrial function during aging, with research demonstrating that carnitine supplementation reverses age-related mitochondrial decline and improves cellular energy metabolism

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2.2.3 Autophagy and apoptosis Autophagy is an early cellular response to METH-induced stress and is activated by the mTOR signaling pathway (Kongsuphol et al., 2009)