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Abrams SL, Evangelisi C, Chiarini F, Misaghian N, Basecke J, Millela M, Tafuri A, Libra M, Stivala F, Konopleva M, Andreeff M , Steelman LS, Troppmair J, Martelli AM, McCubrey JA

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127 In vivo, itaconate accumulation limits bacterial growth and dampens immunopathology, whereas Irg1-deficient mice show increased bacterial burden and excessive inflammation, highlighting its dual role in host defense and immune regulation

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